Though we use a wide range of laboratory methods to gather our data, many of the experiments carried out in our lab involved the following methods:

 

  • Primary Neuron Culture: We culture neuronal cells in vitro to better understand homeostatic scaling in synapses, and how different genotypes lead to variations in synaptic proteomics.

photo of neurons in primary culture

Photo by Bradley Allf

  • Western Blot: We use Western blot to identify proteins in the brain, and to better understand where proteins localize in the brain and synapse.

Image of Western blot

Photo from Wikimedia Commons

  • Animal Behavior: We use the non-invasive Piezo Sleep monitoring system to track sleep in various mouse strains, particularly mouse models of autism spectrum disorder (ASD).

Image of mouse cages in the "Mouse House"

Photo by Bradley Allf